UGT1A1 and cancer: The results showed that the disease remission rate of DW compared with SV during IRI chemotherapy for cancer [OR = 1.65, 95% CI (0.89, 3.05), P = 0.11], the disease remission rate of DW compared with DV [OR = 1.45, 95% CI (0.55, 3.84), P = 0.45] and the disease remission rate of SV compared with DV [OR = 0.56, 95% CI (0.21, 1.50), P = 0.25], none of the above three results were statistically significant (P > 0.05), suggesting that UGT1A1*6 and UGT1A1*28 dual sites have no correlation with IRI efficacy, as shown in Table 2.