ANKRD26 and thrombocytopenia 2: In humans, mutations in 5′-UTR of ANKRD26 have been implicated in the pathogenesis of THC2 (Husnain et al., 2019; Noris et al., 2013, 2011; Perez Botero et al., 1993; Pippucci et al., 2011), although no causative role has been demonstrated in animal models.