Consequently, we tested lysates obtained from full thickness CAL and CAH anastomotic tissues as well as naïve proximal colon tissues for IL-34 (downregulated in CAL compared to CAH) as well as Ccn1, Btnl2 and the TGF-β decoy receptor Bambi (upregulated in CAL versus CAH). The gene discussed is TGFB1; the disease is congenital adrenal hyperplasia.