In our experimental setting IFNGR1 expression on B cells was not very high in the first three days upon infection, therefore we believe it is likely that the increase in Bcl6+ B cells may result from enhanced TFH differentiation following early IFN-γ blockade, whereas the decrease in T-bet+ B cells could be due to IFN-γ action directly on B cells at later time-points. This evidence concerns the gene BCL6 and infection.