Analysis of the expression levels of the 12 transcripts in control cells and NFE2L3 knockdown cells (Fig. 7b) showed that the expression level of LASP1 was the highest in cells, and therefore we hypothesized that NFE2L3 promoted the progression of ccRCC by affecting LASP1 (Supplementary Fig. S4a). This evidence concerns the gene NFE2L3 and nonpapillary renal cell carcinoma.