NFE2L3 and cancer: The acRIP-seq results showed that the abundance of ac4C in NFE2L3 was significantly upregulated in cancer tissues (Fig. 5f), that ac4C modification mainly occurred in the common sequences of CCHCCRCC (H = G or A, R = G or A or U) (Fig. 5g), and that the ac4C modification sites all existed in the CDS region of NFE2L3.