CEMIP and metabolic syndrome: In order to examine the clinical relevance, we examined KIAA1199 plasma levels in a cohort of women that were either lean (LE), overweight (OV), obese (OB) or with metabolic syndrome (MS).20 The expressions of KIAA1199 in SAT were positively correlated with body weight (Fig. S20a), BMI (Fig. S20b), fat mass (Fig. S20c), waist circumference (Fig. S20d), hip circumference (Fig. S20e) and sagittal diameter (Fig. S20f), which was particularly significant in OB + MS and MS group.