CEMIP and Alzheimer disease: To determine whether the observed in vivo reduced fat mass in KO mice caused by the impaired adipocyte (AD) differentiation, primary murine bone marrow MSC (mBMSC) and primary murine adipose tissue derived stromal cells (mADMSC) were isolated from KIAA1199 KO and age-matched WT mice and induced to in vitro AD differentiation.