The HF diet-fed rats displayed significantly (p ≤ 0.01) higher mRNA levels of pro-adipogenic factors such as peroxisome proliferator-activated receptor gamma (PPARγ), CCAAT enhancer binding protein alpha (C/EBPα), sterol regulatory element binding protein 1c (SREBP1c), and HMG CoA reductase (HMGCR) than the control group. Here, SREBF1 is linked to hydrops fetalis.