NCR1 and neoplasm: Immunofluorescence staining of tissue section from tumor-bearing mice revealed NKp46+ cells infiltrating the metastasis in Cxcr3+/+ mice, whereas these cells were predominantly associated with vessels in Cxcr3–/– mice, further supporting CXCR3’s role in NKp46+ cell extravasation and tumor infiltration (Figure 3C).