Compared with other emm types, emm1 was more likely to be associated with a diagnosis of pneumonia (33 of 182 cases [18.1%] vs 29 of 289 cases [10.0%]; OR, 1.99 [95% CI, 1.16-3.40]) and bone or joint infections (46 cases [25.3%] vs 48 cases [16.6%]; OR, 1.70 [95% CI, 1.08-2.68]) but less commonly with bacteremia without focus (30 cases [16.5%] vs 90 cases [31.1%]; OR, 0.43 [95% CI, 0.27-0.68]); emm4 was associated with bacteremia without focus (20 of 31 [64.5%] vs 101 of 440 cases [23.0%]; OR, 6.10 [95% CI, 2.83-13.16]). The gene discussed is PIGG; the disease is bacterial infectious disease with sepsis.