GRAMD1B and infection: As expected, placebo-treated mice and, to a lesser extent, those treated with SF001 at 3 mg/kg, had abscesses filled with fungal hyphae in both the kidneys and brain, whereas mice treated with SF001 at 7.5 or 30 mg/kg or LAMB at 7.5 mg/kg had normal organ architecture with no signs of infection (Fig. 3).