Further, analysis of sequencing data from MMRF‐CoMMpass found that POU2F2, RUNX1, and RUNX2 gene mutations were relatively rare (1.36%, 2.09%, and 0.83%, respectively) among MM patients compared to other tumor types profiled in TCGA, suggesting that their functions are preserved in MM (Figure 7H). This evidence concerns the gene RUNX2 and neoplasm.