Curiously, when we performed RhoGTPase inhibition in serum-free (in the case of RhoA, B and C inhibitor) or low serum (in the case of the Rac1 inhibitor) media, the difference in infection between shScr and shMyo9b #3-expressing U937 cells was reduced (Fig. 4c, d). The gene discussed is RHOA; the disease is infection.