In one early study from the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), a variant in FDFT1 associated with MASLD activity score, another intergenic chromosome 7 variant with fibrosis, and variants in COL13A1, LTBP3, and TFCAB4B with lobular inflammation at P < 1 × 10–06 (26). This evidence concerns the gene COL13A1 and metabolic dysfunction-associated steatohepatitis.