While taking into account that the difference of sFlt-1/PlGF, PlGF, PlGF% and sFlt-1 are much stronger between Group A,C,D and Group B (p < 0.0001) than between Group A and Group D (p < 0.05), the clinical utility of using sFlt-1/PlGF, PlGF, PlGF% and sFlt-1 to predict pregnancy that will deliver low birth weight and/or small-for-gestational age neonates out of healthy pregnancy will be worse than predicting preeclampsia out of healthy pregnancy or pregnancy that will deliver low birth weight/ small-for-gestational age neonates. This evidence concerns the gene PGF and preeclampsia.