The results suggest that for BLCA’s 33 cancers, CXCL12 acts as a significant risk factor for DSS.The result found that high CXCL12 groups have statistically better OS than those for the low CXCL12 groups in CCSK, LUAD, LIHC, LARC, CESE. The gene discussed is CXCL12; the disease is cancer.