BCL6 and diffuse large B-cell lymphoma: We previously synthesized TCIPs that redirect the RNA Polymerase II elongation-associated factors BRD4 and CDK9 to BCL6, a TF that represses pro-apoptotic and growth arrest genes41–43 and is overexpressed in 40 to 60% of diffuse large B cell lymphomas (DLBCLs)44.