TSC1 and neoplasm: The heterogenous functions of different TSC-null EV subtypes are supported by improved 621L9 cell lung seeding (Fig. 6K vs. 6M) and greater lung FAP expression (Fig. 6L) in tumor-free SCID/NOD mice, injected i.v. with tumor TSC-null EV (Fig. 6K), prior to tumor cells injection compared to mice injected with metastasis TSC-null EV (Fig. 6M).