Following subclustering of only CD8-positive T cells (Figure 6C, ≈6600 cells) we identified the predicted tumor-specific clonotypes, including the confirmed tumor- and KRAS Q61H-specific clonotypes from patients 2 and 3, in three of the resulting five clusters (clusters 0, 2, and 3; Figures 6C, D). Here, CD8A is linked to neoplasm.