KRAS and neoplasm: Sequencing of target genomic regions of one representative tumor clone for each pattern revealed that TCR-T cell recognition correlated with the extent of target codon editing (Figure 4B): failed editing resulted in unaltered recognition (clone C9), conservation of only one of the two Q61H-encoding alleles reduced recognition (clone B11), and the successful biallelic codon editing encoding KRAS Q61R (clone G5) resulted in loss of recognition (Figure 4B).