Such findings indicate that CKS1B plays a pivotal role in the pathogenesis of NSCLC, reflecting the complex histopathological processes driven by somatically acquired genetic, epigenetic, transcriptomic, and proteomic alterations responsible for cancer progression (Laurinaviciene et al., 2012; Laurinavicius et al., 2016; Yu and Tian, 2020b). This evidence concerns the gene CKS1B and non-small cell lung carcinoma.