Previous studies have shown that in the tumour environment, CXCL16 has a recruitment effect on monocytes and can promote the transformation of monocytes into macrophages [20], whereas studies on acute coronary syndrome have shown that CXCL16 has a regulatory effect on the secretion of IL-17A and TGF-β, among other factors [21, 22]. This evidence concerns the gene CXCL16 and acute coronary syndrome.