2009). Laboratory indicators may also aid diagnosis, for example, biochemical markers such as lactate dehydrogenase (LDH), glutamic oxalacetic transaminase (ALT), and inflammatory markers such as C‐reactive protein (CRP) may be elevated (R. Zhao et al. 2024). Studies have shown that some biomarkers may be potential biomarkers for the diagnosis of cerebral ischemia‐reperfusion injury, such as 1H NMR metabolomics (Wang et al. 2014), small molecule metabolites (Cheng et al. 2020), and a molecular probe carrying anti‐tropomyosin 4 (Yu et al. 2023). The gene discussed is TPM4; the disease is brain ischemia.