Additionally, the CD30 pathway (TNFSF8 and TNFRSF8), CD40 pathway (CD40LG, ITGA5, ITGAM, ITGB1, ITGB2), and FLT3 signaling pathway (FLT3LG and FLT3) were identified as primary pathways mediating communication between T cells and other immune cells in IPF patients' peripheral blood. The gene discussed is ITGAM; the disease is idiopathic pulmonary fibrosis.