AGRN and neoplasm: To assess this in a scenario that mimics EGFR‐addicted tumor‐thriving conditions, we silenced agrin in both wild‐type and mutant EGFR (del 19) overexpressing H1299 (Figure 3G) and implanted them subcutaneously with soft (≈0.5 kPa) or stiff VitroGel RGD (30 kPa) in SCID mice (Figure 3H).