As observed, Influenza induces IL-8 and granulocyte–macrophage colony-stimulating factor (GM-CSF) secretion by human alveolar epithelial cells through recombinant human Hepatocyte growth factor (HGF)/c-Met and TGF-α/ epidermal growth factor receptor (EGFR) signaling [26]. This evidence concerns the gene CSF2 and influenza.