TGFB1 and liver dysplastic nodule: Collectively, this study points out, for the first time, that FA has the ability to alleviate DN by reactivating the hippo pathway through TGF-β1/Hippo pathway crosstalk modulation which improves its pathogenesis, with superior action of the FA-LNCs25 equivalent to 25 mg/kg/day of FA over the 50 mg/kg/day FA native form.