One prominent example is the expression of genes encoding the BCL-2 family of anti-apoptotic proteins – BCL2, MCL1 and XIAP – which is enhanced by CDK9 activity and thereby enables cancer cell survival in a wide range of tumour types [[88], [89], [90], [91], [92]], including prostate cancer [[50], [86],87]. This evidence concerns the gene BCL2 and Familial prostate cancer.