International clinical data suggests that various oral lesions becomeapparent in the initial 1-4 years preceding the onset of AIDS, likely linked to a diminished CD4 count [36].Numerous studies have identified a reverse association between the CD4 cell count and the prevalence of oral lesions in HIV-positivepatients, where a lower CD4 count (<200/μl) is linked with a higher incidence of oral lesions [21,23-24]. Here, CD4 is linked to AIDS.