Moreover, after obtaining the cut-off value from the ROC curve ofCA125, we found that the coincidence rate of the diagnosis of lymph node metastasis was greater than or close to that of CT diagnosis.Therefore, serum CA125 is more valuable as a biomarker to evaluate endometrial cancer, especially lymph node metastasis, than as adiagnostic tool. Here, MUC16 is linked to endometrial cancer.