In our study, we first analyzed the follow-up survival and mortality groups of patients with DFU, which were differentiated by the mean and percentage of age, PAD, eGFR, and cystatin C. Then, we visualized the survival probability of CKD at different time points by KM curves, and we also compared the difference in the survival probability of different renal function indicators. Here, CST3 is linked to peripheral arterial disease.