Specimen from right adrenalectomy:Pheochromocytoma measuring 6x6 cm (positive for chromogranin 7, synaptophysin +S100, with sustentacular cells staining positive) Marked nuclear pleomorphism: 1 pointDiffuse growth pattern: 2 pointsCapsular invasion: 1 point. Here, SYP is linked to hereditary pheochromocytoma-paraganglioma.