Consistent with the findings in neonatal megakaryocytes (Elagib et al, 2017) and Ewing sarcoma (Mancarella et al, 2018), both JQ1 and dBET1 dose-dependently reduced IGF2BP3 protein levels in WaGa and MKL1 cells (Figure 6a and b). Here, IGF2BP3 is linked to Ewing sarcoma.