Re-analysis of 32,877 single-cell transcriptomes from 11 human glioblastomas41 (IDH-wildtype, CNS WHO grade 4) revealed that IL-6 and IL-6R were expressed by tumor and diverse tumor microenvironment cells, including radial glial cells and other stem, precursor, and progenitor cells (Fig. 6a, b). Here, IL6 is linked to neoplasm.