Interestingly, in patients with ischemic cardiomyopathy (ICM), SNO-BDH1 was decreased and SCoR2 levels were preserved, indicating context-specific regulation (and possibly maladaptive change; Fig. 4S,T, representative SNORAC/Western blot in Fig. S3G,H). This evidence concerns the gene BDH1 and ischemic cardiomyopathy.