In the context of network pharmacology, five constituents of ZGCD—namely lysine, quercetin, gamma-aminobutyric acid, stigmasterol, and beta-sitosterol—are posited to exert anti-diabetic cardiomyopathy (anti-DCM) effects through interactions with the molecular targets ASS1, SERPINE1, CACNA2D1, AVP, APOB, ICAM1, EGFR, TNNC1, F2, F10, IGF1, TNNI2, CAV1, INSR, and INS. This evidence concerns the gene EGFR and diabetic cardiomyopathy.