PIK3R3 and cancer: Additionally, GO database analysis revealed that Kirsten rat sarcoma virus oncogene homologs (KRAS), Erb-B2 receptor tyrosine kinase 2 (ERBB2), phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), mechanistic target of rapamycin kinase (mTOR), myeloid leukemia cell differentiation (MCL1), nucleolin, and spindle-associated protein 1 (NUSAP1) are silenced in miR-193a, implicating their roles in carcinogenesis and cancer progression (12, 51).