miR-99a-5p and miR-100-5p are downregulated in childhood adrenocortical tumors and repress the proliferation of both adrenocortical tumors and pediatric adrenocortical carcinoma cells by targeting mTOR, RAPTOR, and IGF1R (Doghman et al., 2010). This evidence concerns the gene RPTOR and adrenal cortex neoplasm.