While the pathogenesis of Alzheimer’s disease remains to be uncovered, some researchers suggest that insulin resistance prompts the accumulation of both beta-amyloid and tau, therefore suggesting that Alzheimer’s disease is ‘the diabetes of the brain’ or Type 3 diabetes.26 Nonetheless, it should be highlighted this account is still highly disputed. This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.