The results from this work indicate that RNA transport proteins are predominantly shifted to the nucleus in SOD1-G93A mutant cells, suggesting that defects in RNA transport may contribute to ALS pathology.82 Another study focuses on RNA granule transport, highlighting the role of lysosomes and the RNA-binding protein ANXA11 in facilitating long-distance RNA transport in neurons. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.