The patient is a 24-year-old female who was diagnosed with TSC at the age of seven years according to the TSC diagnostic criteria 2021 after the onset of epilepsy [5], cerebral imaging suggestive of SEGAs, renal angiomyolipomas, skin angiofibromas, cardiac leiomyomas, retinal hamartomas and deletion of exons 4-8 in the TSC2 gene detected by multiplex ligation-dependent probe amplification (MLPA) (Table 1). Here, TSC2 is linked to tuberous sclerosis.