IL7R and cancer: Regarding to the genes that showed downregulation, the following were identified: CTAGE1, BDKRB1, SH3RF2, SLC6A12, and IL7R. The CTAGE1 gene encodes an antigen that induces T-cell responses in cancer patients, and it has also been reported to have functionality in Golgi vesicle-mediated transport [90, 91].