Angiotensin-converting enzyme (ACE) inhibitors,angiotensin receptor blockers, and β-blockers can positively influencecardiac remodeling during HF, thereby enhancing patients’ prognoses [18, 19, 20, 21, 22].Simultaneously, numerous large-scale clinical randomized controlled trials (RCTs)have indicated that anti-diabetic drugs also exert a positive impact on theprognosis of HF patients [23, 24, 25, 26, 27, 28, 29, 30]. The gene discussed is ACE; the disease is hydrops fetalis.