COL1A1 and coronary artery disorder: Ong et al. [8] measured 184 CHD-relatedbiomarkers at the plasma level with the proximity extension method, which showedthat collagen type I alpha 1 (COL1A1), bone morphogenetic protein 6(BMP-6), and interleukin-6 receptor subunit alpha(IL-6Rα) were biomarkers in the development of CHD.Biomarkers-based methods can predict CHD, but selecting and collectingCHD-related biomarkers is difficult.