When superoxide anions react withNO to form peroxynitrite, it further enhances the generation of ROS [17, 32].Research studies have found that iNOS expression is not detectable in normalcardiomyocytes; however, its expression is augmented in patients with HF [33].iNOS participates in the oxidative stress process, and the sustained expressionof iNOS leads to a reduction in L-arginine concentration, thereby diminishing NOproduction [34]. The gene discussed is NOS2; the disease is hydrops fetalis.