Figure A represents the analysis of the hub genes for the interaction of the seven compounds and asthma, which revealed that the major hub genes for DBP were PTGS2, ESR1, and CASP3; for DEHP, CASP3, MMP9, BCL2, CCND1, MTOR, PPARG, and BCL2L2; for DEP, the major hub genes were EGFR, TLR4, ACE, and GSK3B; the major hub genes for DIBP were EGFR, CASP3, STAT3, MMP9, and PTGS2; the major hub genes for DINP were EGFR, CASP3, and PTGS2; the major hub genes for DMP were CASP3, EGFR, TLR4, CTSB, and JAK2; the major hub genes for DOP were BCL2, IL 10, HIF1A, PPARG, GSK3B, and PTGS2. This evidence concerns the gene ESR1 and asthma.