Among tumor suppressor family members, the phosphatase and tensin homolog (PTEN) plays an important role in mediating lipid phosphatase activity that antagonizes phosphatidylinositol 3-kinase (PI3K) resulting in the inhibition of the downstream mammalian target of the rapamycin (mTOR)/AKT signaling pathway [1–3]. This evidence concerns the gene PTEN and neoplasm.