SMARCA2 and schizophrenia: For example, many components of the mammalian SWI/SNF complex have now been elucidated in various NDDs, with variants in SMARCA2, SMARCA4, SMARCB1, SMARCE1, ARID1A, and ARID1B having been shown to contribute to a variety of NDDs, such as: Nicolaides-Baraitser syndrome,88,98 Kleefstra syndrome,77,78 Coffin-Siris syndrome,73,99 ASD,44,45 and schizophrenia,50 and with ALS,51,52 among others.