–Lp(a) testing should be considered at least once in a lifetime in adults to identify subjects with an inherited Lp(a) concentration >180 mg/dL (>430 nmol/L) with a whole-life risk fo ASCVD, equivalent ot the risk of heterozygous familial hypercholesterolemia (FHe).–Lp(a) testing should be considered in selected patients with a family history of premature CVD and for reclassification of patients in the moderate-to-high risk limit. The gene discussed is LPA; the disease is familial hypercholesterolemia.