ERN GENTURIS has developed 9 care pathways: NF2-related schwannomatosis, non-NF2 related schwannomatosis, neurofibromatosis type 1, Lynch Syndrome, Hereditary Breast and Ovarian Cancer syndrome, PTEN Hamartoma Tumour Syndrome, Li-Fraumeni and heritable -related cancer, Birt-Hogg-Dubé syndrome, Constitutional Mismatch Repair Deficiency. This evidence concerns the gene NF2 and Hereditary breast and ovarian cancer syndrome.