The DChigh subgroup of DLBCL presented with a significantly lower number of mutations and deletions in senescence gatekeeper gene loci TP53 or CDKN2A52,69, indicative of DC-like plasticity manifesting preferentially in those DLBCL cases that retained functional senescence capacity (Supplementary Fig. 7c). This evidence concerns the gene TP53 and diffuse large B-cell lymphoma.