CD4 and systemic lupus erythematosus: We assessed five different Treg subtypes, phenotypically defined as (i) CD4+ CD25+ CD127−, (ii) CD4+ CD25+ CD127− IL-10+, (iii) CD4+ IL-10+, (iv) CD4+ FOXP3+ and (v) CD4+ FOXP3+ IL-10+ by flow cytometry in the isolated PBMCs of SLE patients.